Write to them in care of this newspaper or e-mail them via their Web site: . Background: Grapefruit juice greatly increases the bioavailability of lovastatin and simvastatin.
In their column, Joe and Teresa Graedon answer letters from readers. Grapefruit juice affects certain statins more than others. One study did suggest that there is an effect on the immune system that might help relieve allergic symptoms (Bioscience, Biotechnology and Biochemistry, October 2001). It has been used traditionally against pollen allergies, but there is not a lot of clinical research to support its effectiveness. We have heard of rooibos tea ("red bush" tea) from South Africa. Effects of grapefruit juice on intestinal P-glycoprotein. Drinking grapefruit juice while taking certain 'statins' might increase the effects and side effects of these medications. Now that I am back home in Houston, my usual fall allergies have not appeared. Medications used for lowering cholesterol (Statins) Grapefruit juice might decrease how quickly the body breaks down some 'statin' medications. While in Africa, I started drinking rooibos tea every day. In some cases, rhabdomyolysis can cause kidney damage and even death. This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. It may also help prevent atherosclerosis and certain cancers. Grapefruit juice can increase the blood levels of atorvastatin. Some research indicates that turmeric and its primary component, curcumin, can ease the inflammation of psoriasis and arthritis (Current Opinion in Pharmacology, June 2007). Grapefruit juice can increase levels of drugs metabolized by CYP3A4. Its medicinal properties have been recognized for nearly that long. Several available statins do not interact with grapefruit juice and are safe to use. Atorvastatin Calcium is classified as belonging to the following category: Cytochrome P450 3A4 (Cyp3A4) Substrates. Turmeric has been used to season food for thousands of years.
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